Abstract
This article reviews current methods of extracorporeal therapy for the treatment of sepsis, with emphasis on innovative hemosorption filters such as Seraph 100 Microbind Affinity, GARNET and Hemopurifier. Sepsis is a serious condition associated with an uncontrolled immune response to infection, often resulting in organ failure and high mortality. Conventional methods, including antimicrobial therapy, may not be sufficient in infections caused by resistant pathogens. Hemosorption filters work by removing pathogens and their mediators from the blood, reducing the risk of cytokine storm and improving clinical outcomes. Studies show the efficacy of these devices in the treatment of complex infections including bacteremia and viremia; however, additional large clinical trials are needed to confirm their safety and optimal indications for use.
For citation: Shingur VV, Spichka II. Extracorporeal therapy of sepsis — target change. USMU Medical Bulletin. 2025;10(1):e00136. (In Russ.). DOI: https://doi.org/10.52420/usmumb.10.1.e00136. EDN: https://elibrary.ru/FYANSS.
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