Keywords
young adults
long-term prognosis
follow-up
recurrent stroke
disability
mortality
Abstract
Introduction. The long-term prognosis of ischemic stroke (IS) in young adults is insufficiently studied, despite the growing social and economic significance of this problem.
Objective is to analyze the rates of mortality, recurrence, and disability over a 10-year period in patients who experienced IS at a young age.
Materials and methods. A retrospective cohort study was conducted. Data from 128 patients aged 18 to 44 years who suffered an IS in 2013 in Ekaterinburg were included. Information on long-term outcomes was collected for 103 patients based on the analysis of medical records and telephone interviews. The primary endpoints were all-cause mortality, recurrent IS rate, and disability at 10 years.
Results. The proportion of IS in young patients was 3.4 % of all stroke cases. Over the 10-year follow-up period in the tracked cohort (n = 103), cumulative mortality reached 9.7 %, with 40.0 % of deaths caused by recurrent stroke. The 10-year recurrence rate of IS was 19.4 %. A long-term disability status was officially registered in 32.0 % of patients by the end of the follow-up period.
Conclusion. Ischemic stroke in young adults is associated with a high risk of adverse long-term outcomes, including significant rates of mortality, recurrent vascular events, and permanent disability. These findings highlight the serious socio-economic burden of the condition and indicate the need to optimize long-term secondary prevention and rehabilitation strategies for this patient category.
For citation
Smirnov DA, Shavalieva EV. Long-term follow-up of patients after ischemic stroke at a young age. USMU Medical Bulletin. 2025;10(4):e00189. (In Russ.). DOI: https://doi.org/10.52420/usmumb.10.4.e00189. EDN: https://elibrary.ru/CVEDDN.
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