The Role of Neutrophils in Cancer Prognosis and Possible Points for Therapeutic Interventions
No. 3–4 (2022), Science and Practice
No. 3–4 (2022)

The Role of Neutrophils in Cancer Prognosis and Possible Points for Therapeutic Interventions

Science and Practice
Published 20.12.2022
Anna K. Golubtsova
Ural State Medical University
Evgeniya B. Kantysheva
Ural State Medical University
Anastasia V. Novoselova
Ural State Medical University
Mikhail V. Popugaylo
Ural State Medical University
https://orcid.org/0000-0003-4820-5964
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Keywords

neutrophils
cancer
extracellular traps
biomarkers
cancer therapy

Abstract

This review examines the complex role of neutrophils in the pathogenesis of cancer. Neutrophil extracellular traps and the ratio of neutrophils to lymphocytes may indicate the degree of malignancy of the tumor and have great prognostic value. Neutrophils, as well as the impact on their metabolic pathways, are a promising direction in cancer immunotherapy.

PDF (Русский)
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Copyright © 2022 Голубцова А. К., Кантышева Е. Б., Новосёлова А. В., Попугайло М. В.